Actualités

Ifigeneia Mavranezouli ^1 2,  Odette Megnin-Viggars ^1 2,  Nick Gray ^3 4,  Gita Bhutani ^5 6,  Jonathan Leach ⁷,  Caitlin Daly ⁸,  Sofia Dias ⁸,  Nicky J Welton ⁸,  Cornelius Katona ^9 dix,  Sharif El-Leithy ¹¹,  Neil Greenberg ¹²,  Sarah Stockton ²,  Stephen Pilling ^1 2 13.

PLoS One. 2020 Apr 30;15(4):e0232245. doi: 10.1371/journal.pone.0232245. eCollection 2020.PMID: 32353011 

Abstract

Background: Post-traumatic stress disorder (PTSD) is a severe and disabling condition that may lead to functional impairment and reduced productivity. Psychological interventions have been shown to be effective in its management. The objective of this study was to assess the cost-effectiveness of a range of interventions for adults with PTSD.

Methods: A decision-analytic model was constructed to compare costs and quality-adjusted life-years (QALYs) of 10 interventions and no treatment for adults with PTSD, from the perspective of the National Health Service and personal social services in England. Effectiveness data were derived from a systematic review and network meta-analysis. Other model input parameters were based on published sources, supplemented by expert opinion.

Results: Eye movement desensitisation and reprocessing (EMDR) appeared to be the most cost-effective intervention for adults with PTSD (with a probability of 0.34 amongst the 11 evaluated options at a cost-effectiveness threshold of £20,000/QALY), followed by combined somatic/cognitive therapies, self-help with support, psychoeducation, selective serotonin reuptake inhibitors (SSRIs), trauma-focused cognitive behavioural therapy (TF-CBT), self-help without support, non-TF-CBT and combined TF-CBT/SSRIs. Counselling appeared to be less cost-effective than no treatment. TF-CBT had the largest evidence base.

Free PMC article l

Source : 10.1371 / journal.pone.0232245